Trimetazidine (Generic Vastarel®) Is Used In The Treatment Of Ischaemic
Heart Disease (Angina Pectoris, Sequelae Of Infarction).
Trimetazidine is a drug for angina pectoris sometimes referred to by the
brand name Vastarel MR. Each tablet contains 35 mg of trimetazidine.
Trimetazidine is an anti-ischemic (anti-anginal) metabolic agent, that
improves myocardial glucose utilization through inhibition of Fatty acid
metabolism.
By preserving the energy metabolism in cells exposed to hypoxia or
ischemia, trimetazidine prevents a decrease in intracellular adenosine
triphosphate levels, thereby ensuring the proper functioning of ionic
pumps and transmembranous sodium-potassium flow whilst maintaining
cellular homeostasis.
Controlled studies in angina patients have shown that trimetazidine
increases coronary flow reserve, thereby delaying the onset of ischemia
associated with exercise, limits rapid swings in blood pressure without
any significant variations in heart rate, significantly decreases the
frequency of angina attacks, and leads to a significant decrease in the
use of nitrates.
It improves left ventricular function in diabetic patients with coronary
artery disease. Recently, it has been shown to be effective in patients
with heart failure of different etiologies.
It is described as the first cytoprotective anti-ischemic agent, acts by
directly counteracting all the major metabolic disorders occurring within
the ischemic cell. The actions of trimetazidine include limitation of
intracellular acidosis, correction of disturbances of transmembrane ion
exchanges, and prevention of excessive production of free radicals.
It is usually prescribed as a long-term treatment of angina pectoris, and
in some countries (including France) for tinnitus and dizziness.
Vastarel MR is also distributed as: Vastarel 35 mg, Vastarel LM, Vastarel
LP, Preductal MR, Flavedon MR and Trizedon MR.
Where can i order Vastarel ?
We only recommend on the most reliable, International (ship to worldwide) pharmacies (No Prescription
Needed) that got great feedback from our
readers:
Vastarel medicine is a life saver (for my angina :) ) Thank you. Russell
As for today, I don't know how i lived before i discover that medicine
it's a godsend. Michael
I am very pleased with Vastarel, It's the best med for angina .
Sara.
Does what it is supposed to do. Side effects minimal and tolerable A+.
Spencer.
*The testimonials shown above are based on actual letters we received from
our many satisfied customers that read this page of review and bought
Vastarel.
