Drug Class And Mechanism: Verapamil belongs to a class of medications
called calcium channel blockers. These medications block the movement of
calcium into the muscle cells of the coronary arteries (the arteries
supplying the heart) as well as the other arteries of the body. Since
calcium is what triggers contraction of muscles, blocking entry of calcium
relaxes the arterial muscles. This relaxation allows the arteries to
become larger so that more blood can flow through them. Thus, verapamil is
useful in treating and preventing chest pain (angina) resulting from spasm
(contraction) of the coronary arteries that reduces the flow of blood to
the heart. Relaxing the muscles lining the arteries in the rest of the
body lowers blood pressure and thereby reduces the pressure against which
the heart must pump blood. As a result, the heart works less and requires
less oxygen-carrying blood. This allows the heart to work with the reduced
flow of blood caused by coronary artery disease and prevents angina (which
occurs whenever the flow of blood to the heart is inadequate). For more
detailed information related to coronary artery disease, please read the
Chest Pain, Cholesterol, and Heart Attack articles. Verapamil also
decreases the conduction of electrical impulses through the heart that
control the coordination of contraction. As a result, the rate of
contraction slows. Verapamil was approved by the FDA in March, 1982.
Prescribed For: Chest pain (angina) occurs because insufficient
oxygen-carrying blood is delivered to the muscles of the heart.
Insufficient oxygen-carrying blood may be a result of blockage of blood
flow in the coronary arteries due to coronary artery disease or spasm, or
an increase in physical exertion that increases the workload of the heart
and the demand by the heart for oxygen. Verapamil is used for the
treatment and prevention of angina resulting from coronary artery disease
and spasm as well as from exertion. Verapamil also is used in the
treatment of high blood pressure. Verapamil slows electrical conduction of
the electrical impulses through the heart and has been used to in treat
abnormally fast heart rhythms such as atrial fibrillation, and in the
prevention of recurrent episodes of rapid heart rhythm originating from
the atria.
Storage: Store at room temperature 15° to 30°C (59° to 86°F) in tight,
light- resistant container.
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My tachycardia first started at age 11 and I had 4-8 episodes per year
until starting Verapamil about ten years ago. I have perhaps one or two
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I've suffered from migraines for over 14 years and this is the only thing
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Cannot get it anymore. What gives. I really liked it. Neither the mail
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*The testimonials shown above are based on actual letters we received from
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